Renue By Science Trigonelline | High Strength Trigonelline TRG Methylated Niacin - 250mg Trigonilline Supplement Capsules | Non-GMO | Made in The USA & Third-Party Tested

Description

Trigonelline is a unique NAD+ precursor that can survive through the acid and enzymes of the digestive process to be absorbed into the bloodstream intact. Since it is so highly bioavailable, it can be delivered to tissues throughout the body and absorbed into cells to be utilized in the synthesis of NAD+ using the Preiss-Handler pathway, while other NAD+ precursors primarily use the Salvage pathway. By directly impacting NAD+ synthesis in tissues throughout the body, Trigonelline can protect youthful function of organ systems like the brain and the heart, supporting cognition and circulation. It can also protect skeletal muscle strength as well as regulation of healthy blood lipid and sugar metabolism. Renue By Science has been driving longevity research forward since its foundation, and continues to innovate with novel molecules and the most effective delivery systems. Each batch of every product is rigorously tested by third-party labs and backed by clinical research to provide quality and effectiveness that isnt available anywhere else.

Features

• Muscle NAD+ Synthesis: By promoting NAD+ synthesis in muscle through the Preiss-Handler pathway, Trigonelline enhances cellular energy and repair, supporting overall health and longevity. Supports muscle NAD+ production, unlike NMN or NR. It provides the precursors needed to generate NAD+ that becomes depleted through cellular metabolism and aging.
• DNA Repair and Cellular Integrity: Encouraging cellular repair and maintaining DNA integrity, Trigonelline protects against cellular damage and promotes health at the molecular level. Additionally donates methyl groups which promote healthy gene expression.
• Protects Against Tissue Aging: Supplies much-needed NAD+ precursors to tissues like the heart, brain, and muscles. NAD+ declines fastest in tissues that experience the most oxidative damage and physiological use, so using Trigonelline to refuel these tissues protects youthful heart, brain, and muscle function, preserving strength and cognition.
• Broad Longevity Support: Unlike other NAD+ precursors, Trigonelline is stable through digestion and enters circulation for systemic tissue delivery. Once in circulation it can support healthy sugar and lipid metabolism and does not cause the flushing effect that many experience with niacin.
• Naturally Occurring NAD+ Support: Trigonelline is found in numerous plant foods including coffee and fenugreek. This highly bioavailable and stable molecule can cross the blood-brain barrier and is quickly metabolized into NAD+, measurably impacting circulating and intracellular levels of this critical molecule.